All products have special prices for bulk purchase, please contact for more details if required.

For RNasin with higher antioxidant activity, please visit Murine RNase Inhibitor, which is more suitable for downstream experiments sensitive to reducing agents such as DTT.

For RNasin with higher affinity, heat resistance, and antioxidant/anti-sulfhydryl activity, please visit PrimeIAmp™ RNasin (RNase inhibitor). The glycerol-free version is also available.

Cat. No.: FRN-1k (for 1KU)

Cat. No.: FRN-100k (for 100KU)

Description

RNasin (RNase inhibitor) is a ribonuclease inhibitor extracted from human placenta with a molecular weight 51 kDa. It inhibits the activity of RNase by specifically binding up to RNase with a non-covalent bond. RNasin, free of RNase or Nickase, can maintain its activity at pH from 5 to 8, with the highest activity at pH 7.8. The concentration of RNasin is 20~40 units/µl.

Function

RNasin (RNase inhibitor) can be used in almost any application where RNase contamination may exist. Our high-quality RNasin can inhibit RNase more extensively than many traditional RNase inhibitors, so it has become a better choice of RNase inhibitor at present, which can provide a higher level of protection against RNA degradation.

Unit Definition                           

One unit is defined as the amount of enzyme required to inhibit 50% activity of 5 ng RNase A.

Storage

Stored at -20°C.

Instruction: RNasin Instruction

Related: Murine RNasin, PrimeIAmp™ RNasin (RNase inhibitor)

Featured Citations

Interested in seeing published research using our RNasin?

Recovering circulating extracellular or cell-free RNA from bodily fluids

^{_{Cancer Epidemiology    |     22 Apr 2011    |    DOI: https://doi.org/10.1016/j.canep.2011.02.016}}

^{_{Some inhibitors are to be used for RNA isolation (RNAlater by Ambion, Qiagen, Superase-in by Ambion) (Table 1), and others are most effective as prophylactics during enzymatic reactions (Ribonuclease Inhibitor (Recombinant) by Affymetrix, RNasin® Plus RNase Inhibitor and Recombinant RNasin® Ribonuclease Inhibitor by Promega, RNasin, Electrophoresis by SBS Genetech}}

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Only for research and not intended for treatment of humans or animals

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SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory