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Cat. No.: RIGFH-10 (for 10μg)

Cat. No.: RIGFH-25 (for 25μg)

Cat. No.: RIGFH-50 (for 50μg)

Cat. No.: RIGFH-100 (for 100μg)

Cat. No.: RIGFH-1k (for 1mg)

Description

The fragment crystallizable (Fc) region is the tail portion of an antibody that interacts with cell surface receptors known as Fc receptors, as well as certain proteins in the complement system. This region enables antibodies to activate the immune system, such as by binding to Fc receptors. Through its binding to various cell receptors and complement proteins, the Fc region mediates a range of physiological effects of antibodies, including the detection of opsonized particles, cell lysis, and the degranulation of mast cells, basophils, and eosinophils, among other processes.

Species

Rabbit

Accession

P01870-1

Expression Sequence

Protein sequence (P01870-1, Cys105-Lys323, with C-10*His)

CPPPELLGGPSVFIFPPKPKDTLMISRTPEVTCVVVDVSQDDPEVQFTWYINNEQVRTARPPLREQQFNSTIRVVSTLPITHQDWLRGKEFKCKVHNKALPAPIEKTISKARGQPLEPKVYTMGPPREELSSRSVSLTCMINGFYPSDISVEWEKNGKAEDNYKTTPAVLDSDGSYFLYNKLSVPTSEWQRGDVFTCSVMHEALHNHYTQKSISRSPGKGGGGSHHHHHHHHHH

Expression Host

HEK293

Molecular Weight

Predicted MW: 26.5 kDa 

Observed MW: 30 kDa

Purity

＞95% by SDS-PAGE

Tag

with C-10*His

Form

Lyophilized Powder

Buffer System

Lyophilized from a 0.2 μm filtered solution of 0.2M PBS, pH7.4.

Reconstitution Method

Reconstitute no more than 1 mg/mL according to the size in deionized water after rapid centrifugation.

Storage Conditions

12 months from the date of receipt when stored at -20 to -70 °C as supplied.

6 months at -20 to -70 °C under sterile conditions after reconstitution.

1 week at 2 to 8 °C under sterile conditions after reconstitution.

Please avoid repeated freeze-thaw cycles.