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Cat. No.: PAIAN5C3-500 (for PAI Antibody-5C3, 500μg)

PAI Antibody-5C3

• Clone: 5C3
• Source: Mouse

Description

Plasminogen Activator Inhibitor (PAI) is a regulatory protein that plays a pivotal role in the fibrinolysis process. It functions by inhibiting plasminogen activators, including tissue-type plasminogen activator (tPA) and urokinase-type plasminogen activator (uPA), thereby modulating and limiting fibrinolysis. PAI is essential for maintaining the delicate balance between coagulation and fibrinolysis within the body. Abnormal levels of PAI are often linked to thrombotic or hemorrhagic disorders. Consequently, variations in PAI levels serve as valuable indicators of the functional status of the fibrinolysis system, offering critical insights into its activity and potential dysregulation.

Specificity

Human PAI

Isotype

IgG

Form

Liquid 

Buffer

0.01M PBS, pH 7.4, 0.1% Proclin300

Purification Method

Affinity purified

Purity

≥90% by SDS-PAGE

Storage

Shipped at 2-8 °C. Upon delivery aliquot and store at-20°C±5°C. Avoid freeze/thaw cycles.

Application: CLIA

Matters Needing Attention

This product contains preservative. Standard Laboratory Practices should be followed when handling this material.

Note

Centrifuge before opening to ensure vial contents are completely collected.

Only for research and not intended for treatment of humans or animals

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