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Cat. No.: ECML-50 (for 50 μg)

Cat. No.: ECML-200 (for 200 μg)

The lyophilized E.coli MutL Protein is also available by inquiry, which can be transported at room temperature.

Description

DNA mismatch repair system (MMR) is mainly composed of three proteins, including MutS, MutL, and MutH. Among them, MutS is responsible for recognizing and binding to mismatched or unbound sites. Subsequently, MutL protein forms a complex with MutS-DNA to enhance its stability, activate the endonuclease activity of MutH, and cooperate with helicase and single-strand binding protein to remove the mismatched sequence. E.coli MutL protein has DNA dependent ATPase activity and can mediate MutS and UvrD to play a role in DNA mismatch repair, so it plays an important role in DNA mismatch repair.

Components

50 μg

E.coli MutL Protein (0.5 μg/μl):    100 μl

Storage

The minimum shelf life is 3 years at -20°C.

Note

• Storage Buffer: 20mM Tris-HCl (pH7.5), 200mM NaCl, 5mM DTT, 25% glycerol.