All products have special prices for bulk purchase, please contact for more details if required.

Cat. No.: DFSDP4-100 (for 100U)

Cat. No.: DFSDP4-500 (for 500U)

Description

DNA-Free Sulfolobus DNA Polymerase IV is a thermostable Y-family DNA polymerase capable of bypassing DNA damage during replication, thus synthesizing DNA using various damaged DNA templates. Sulfolobus DNA polymerase IV can incorporate incorrect bases during DNA replication, leading to base mutations. Additionally, it can cause template base slippage, resulting in base deletions. Due to its low fidelity, it is suitable for error-prone PCR to increase the random mutation rate.

Our DNA-Free Sulfolobus DNA Polymerase IV is a recombinant protein and purified through multiple steps, devoid of genomic and plasmid DNA from the production strain.

Unit Definition

One unit is defined as the amount of enzyme required to incorporate 10 nmol dNTP into acid-insoluble material within 30 minutes at 55℃ in 1× Polymerase Buffer.

Features

• Completely free from bacterial DNA.
• Strong tolerance to damaged template bases.
• Capable of replicating DNA templates with damage.

Applications

• Translesion synthesis of damaged DNA templates.
• Random mutation of normal template DNA.
• Low-fidelity gap filling (without strand displacement and nick translation activities).

SBS Genetech is recognized as one of the global major leading industry players in DNA Polymerase by third-party market researchers. For more details, please visit DNA Polymerase Market Size To Reach USD 568.3 Million In 2030 | Rising Demand For Customized DNA Polymerase And Next-Generation DNA Sequencing Are Some Of The Key Factors Driving Market Revenue Growth, Says Reports and Data

Only for research and not intended for treatment of humans or animals

Journals Using SBS Genetech Products                                       Universities Using SBS Genetech Products

SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory