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Cat. No.: CTAN-100 (for cTnI Antigen, 100μg)

cTnI Antigen

• Protein Type: Recombinant, with his tag.
• Molecular Weight: 26kDa
• Source: E.coli

Description

Troponin (Tn) is a regulatory protein for muscle contraction, located in the fine filaments of contractile proteins, where it regulates muscle contraction and relaxation. It has three subtypes: fast-response, slow-response, and cardiac troponin (cTn). The first two are linked to skeletal muscle, while cTn is exclusive to cardiomyocytes and consists of three subunits: troponin T (cTnT), troponin I (cTnI), and troponin C (cTnC). cTnI, unique to cardiomyocytes, contains 210 amino acids and has a molecular weight of 23.88 KDa. When cardiomyocytes are damaged, cTnI is released from myocardial fibers. Elevated cTnI levels in serum indicate cardiomyocyte injury, with higher specificity and sensitivity than standard myocardial enzyme profiles. Troponin is a key marker for myocardial injury and necrosis, playing a critical role in diagnosing and risk-stratifying acute myocardial infarction (100% sensitivity, 91% specificity, and long detectability).

Form

Liquid 

Buffer

0.01M PBS, pH 7.4

Purification Method

Affinity purified 

Purity

≥ 90% by SDS-PAGE

Storage

Shipped at 2-8 ℃. Upon delivery, aliquot and store at -20±5℃. Avoid freeze/thaw cycles.

Application

Calibrator or standard in immunoassays.

Note

Centrifuge before opening to ensure vial contents are completely collected.

Only for research and not intended for treatment of humans or animals

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