All products have special prices for bulk purchase, please contact for more details if required.

Cat. No.: CA2C5-500 (for cTnI Antibody -2C5, 500μg)

Cat. No.: CA2E3-500 (for cTnI Antibody -2E3, 500μg)

Cat. No.: CA4C7-500 (for cTnI Antibody -4C7, 500μg)

Cat. No.: CA2E9-500 (for TnC Antibody -2E9, 500μg)

Cat. No.: CA7E2-500 (for CTnI Antibody-7E2, 500μg)

Cat. No.: CA2C7-500 (for CTnI Antibody-2C7, 500μg)

cTnI Antibody -2C5

• Clone: 2C5
• Source: CHO
• Isotype: Mouse IgG1
• Specificity: Cardiac troponin I

cTnI Antibody -2E3

• Clone: 2E3
• Source: CHO
• Isotype: Rabbit IgG
• Specificity: Cardiac troponin I

cTnI Antibody -4C7

• Clone: 4C7
• Source: CHO
• Isotype: Mouse IgG2b
• Specificity: cTnI- TnC complex

Application: ELISA，LFIA

Description

Troponin (Tn) is a regulatory protein for muscle contraction, located in the fine filaments of contractile proteins, where it regulates muscle contraction and relaxation. It has three subtypes: fast-response, slow-response, and cardiac troponin (cTn). The first two are linked to skeletal muscle, while cTn is exclusive to cardiomyocytes and consists of three subunits: troponin T (cTnT), troponin I (cTnI), and troponin C (cTnC). cTnI, unique to cardiomyocytes, contains 210 amino acids and has a molecular weight of 23.88 KDa. When cardiomyocytes are damaged, cTnI is released from myocardial fibers. Elevated cTnI levels in serum indicate cardiomyocyte injury, with higher specificity and sensitivity than standard myocardial enzyme profiles. Troponin is a key marker for myocardial injury and necrosis, playing a critical role in diagnosing and risk-stratifying acute myocardial infarction (100% sensitivity, 91% specificity, and long detectability).

Form

Liquid

Buffer

• 2C5: 0.01 M PBS, pH7.4, 0.1% proclin 300
• 2E3: 0.01 M PBS, pH7.4, 0.1% proclin 300 
• 4C7: 0.01 M PBS, pH8.0, 0.1% Proclin 300
• 2E9: 0.01 M PBS, pH8.0, 0.1% Proclin 300
• 7E2: 0.01M PBS, pH 7.4, 0.1% Proclin300 
• 2C7: 0.01M PBS, pH7.4，0.2% Proclin300

Purification Method

Affinity purified

Purity

≥95% by SDS-PAGE

Storage

Shipped at 2-8 ℃. Upon delivery, aliquot and store at -20±5℃. Avoid freeze/thaw cycles.

Matters Needing Attention

This product contains a preservative. Standard Laboratory Practices should be followed when handling this material.

Note

Centrifuge before opening to ensure vial contents are completely collected.

Only for research and not intended for treatment of humans or animals

Journals Using SBS Genetech Products                                       Universities Using SBS Genetech Products

SBS Genetech is a long-term sponsor of Cold Spring Harbor Laboratory