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Cat. No.: 5EU-50 (for 50mg)

Cat. No.: 5EU-250 (for 250mg)

Cat. No.: 5EU-1k (for 1g)

Description

5-Ethynyl uridine (EU) is a novel alternative for bromo uridine (BrU or BrUTP) and can be used to measure RNA synthesis in proliferating cells. EU can be efficiently incorporated into RNA by several polymerases, but it does not incorporate into DNA. Detection of the incorporated EU is based on a powerful click chemical reaction with fluorescent dyes. The click detection reaction requires copper as the catalyst. The cells can be analyzed by fluorescence imaging, flow cytometry, or high content imaging analysis.

Product Information

• Chemical name: 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-ethynylpyrimidine-2,4(1H,3H)-dione
• Abbreviation: 5-EU, EU
• Synonyms: 5-Ethynyl Uridine, 5-EU
• Chemical formula: C11H12N2O6
• Molecular weight: 268.22
• CAS number: 69075-42-9
• Purity: ≥98%
• Solvent/Solubility: Soluble in DMSO (100~1000mM), water (50~100mM).
• Solution preparation: Dissolve 5mg in 1.86ml DMSO, or dissolve 2.68mg in 1ml DMSO to prepare a 10mM solution.

Storage

Store at -20°C. The product is effective for one year.

Note

• This product is intended for scientific research purposes by professionals only. It is not to be used for clinical diagnosis or treatment, nor for food or drug purposes. It should not be stored in residential areas.
• For your safety and health, please wear laboratory attire and disposable gloves while handling.

Only for research and not intended for treatment of humans or animals

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